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Drupal
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add to my toolboxVery extensible CMS platform based on PHP and used by many NGOs - "Community Plumbing"
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Firefox
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add to my toolboxFirefox is the popular open source web browser from Mozilla
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Skype
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add to my toolboxFree/cheap Internet telephony and handy IM tool.
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Audacity
in 96 toolboxes
add to my toolboxFree, open source software for recording and editing sounds.
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Mac OS X
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add to my toolboxApple's desktop operating system.
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Adium
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add to my toolboxAdium is a free instant messaging application for Mac OS X that can connect to AIM, MSN, Jabber, Yahoo, and more.
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VLC Media Player
in 79 toolboxes
add to my toolboxVLC media player is a highly portable multimedia player for various audio and video formats (MPEG-1, MPEG-2, MPEG-4, DivX, mp3, ogg, ...) as well as DVDs, VCDs, and various streaming protocols.